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Therapeutic Efficacy, Biomarker Signatures and Translatability of Semaglutide in the Liver Biopsy-Confirmed GAN DIO-MASH Mouse Model (study 7/9)

ABSTRACT: To investigate the effect of treatment duration on therapeutic efficacy, semaglutide was administered in the GAN-DIO MASH mice. Endpoints included body weight, plasma biochemistry as well as liver histological and transcriptome assessments.

ORGANISM(S): Mus musculus

PROVIDER: GSE301751 | GEO | 2026/04/14

REPOSITORIES: GEO

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Therapeutic Efficacy, Biomarker Signatures and Translatability of Semaglutide in the Liver Biopsy-Confirmed GAN DIO-MASH Mouse Model (study 6)

Project description:12-week semaglutide treatment was characterized in the GAN-DIO MASH mice. Endpoints included body weight, plasma biochemistry and proteomics as well as liver histological and transcriptome assessments.

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