Transcriptome Reprogramming Associated with Autoimmunity Reveals Key Points of the Growth-Defence Trade-off in Arabidopsis thaliana
Ontology highlight
ABSTRACT: Growth and defence are inversely correlated processes requiring balance for optimal fitness. Using DANGEROUS MIX (DM) autoimmune plants with stunted growth in Arabidopsis thaliana, we investigated the balancing act through transcriptome analysis of three DM cases and identified two major modules representing defence and growth. Removing all three ADR1s (helper NLRs) reversed the expression patterns and shifted the trade-off balance, revealing ADR1s' dual role in enhancing immune responses and actively suppressing growth-related genes.
ORGANISM(S): Arabidopsis thaliana
PROVIDER: GSE301889 | GEO | 2025/08/26
REPOSITORIES: GEO
ACCESS DATA