DNA Methylation and Hydroxymethylation Profiles in Paneth cell from Germ-Free and SPF Mice

ABSTRACT: To assess epigenetic effects, Paneth cell–specific Nanopore sequencing was performed on germ-free (GF) and specific pathogen–free (SPF) mice. Our analysis reveals microbiome-driven changes in 5mC and 5hmC at key genetic loci involved in stemness regulation.

ORGANISM(S): Mus musculus

PROVIDER: GSE301987 | GEO | 2026/07/09

REPOSITORIES: GEO