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Analysis of gene expression after CRISPR-mediated activation of TEDAR (LINC00302) lncRNA in primary human keratinocytes

ABSTRACT: Long non-coding RNAs (lncRNAs) are emerging as key regulators of epidermal differentiation. To investigate the function of the skin-enriched lncRNA TEDAR (LINC00302), we performed CRISPR-mediated activation in primary human keratinocytes and profiled global gene expression using the Affymetrix Clariom D Human microarray platform. Differential expression analysis demonstrated that TEDAR regulated genes involved in late epidermal differentiation and barrier formation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE302073 | GEO | 2026/07/01

REPOSITORIES: GEO

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