CXCL5 inhibition suppresses gastric mixed neuroendocrine-non-neuroendocrine neoplasms arising from transformed Pou2f3+ epithelium

ABSTRACT: To explore the possibility that tumor development relies on a shared oncogenic facilitator rather than on specific SOX2 or SOX9 expression patterns, we performed bulk RNA sequencing of gastric tumors from Pou2f3-CreERT; Rb1fl/fl; Trp53fl/fl; LSL-MycT58A mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE302588 | GEO | 2025/07/18

REPOSITORIES: GEO