Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq profiling of Pleurotus ostreatus exposed to BBP with or without cytochrome P450 inhibition

ABSTRACT: This study provides transcriptomic insights into the degradation of butyl benzyl phthalate (BBP) by the white-rot fungus Pleurotus ostreatus. RNA-seq was conducted for samples treated with BBP alone or in combination with the cytochrome P450 inhibitor piperonyl butoxide (PB). The aim was to investigate the role of fungal enzymes in BBP metabolism. Differentially expressed genes related to xenobiotic degradation, oxidative stress, and P450 activity were identified and analyzed.

ORGANISM(S): Pleurotus ostreatus

PROVIDER: GSE302615 | GEO | 2025/08/01

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Impact of transposable elements in Pleurotus ostreatus transcriptome profiles

Project description:Pleurotus ostreatus, also known as the oyster mushroom, is an active lignin decomposer in the forests. The genomes of the monokaryotic strains PC15 and PC9 have been used to characterize the content and distribution of transposable elements. This study analyzes the impact of transposable element insertions on the global transcriptome of P. ostreatus. The transcriptome of PC15 and PC9 has been analyzed in exponential growth during submerged fermentation in malt-yeast extract-sucrose medium RNAseq of two P. ostreatus strains: PC15 and PC9

2016-05-19 | E-GEOD-81586 | biostudies-arrayexpress

RNA-seq profiling of Pleurotus ostreatus exposed to BBP with or without cytochrome P450 inhibition

Project description:RNA-seq profiling of Pleurotus ostreatus exposed to BBP with or without cytochrome P450 inhibition

| PRJNA1291594 | ENA

Impact of transposable elements in Pleurotus ostreatus transcriptome profiles

2016-05-19 | GSE81586 | GEO

Transcriptomes of Pleurotus ostreatus in four different development stages (mycelium, primordium, young fruit body, mature fruit body)

Project description:To elucidate the mechanisms of fruit body development in Pleurotus ostreatus, the transcriptomes of four different development stages including mycelium, primordium, young fruit body, and mature fruit body were obtained by RNA-seq.

2018-04-12 | GSE113026 | GEO

Piperonyl butoxide induces the expression of P450 and GST genes in Drosophila melanogaster

Project description:Piperonyl butoxide (PBO) is an insecticide synergist known to inhibit the activity of cytochrome P450 enzymes. PBO is currently used in many insecticide formulations, and has also been suggested as a pre-treatment in some pesticide applications. Little is known about how insects respond to PBO exposure at the gene transcription level. We have characterised the transcriptional response of the Drosophila melanogaster genome after PBO treatment, using both a custom designed “detox” microarray containing cytochrome P450 (P450), glutathione S-transferase (GST) and esterase genes, and a full genome microarray. We identify a subset of P450 and GST genes, along with additional metabolic genes, that are highly induced by PBO. The gene set is an extremely similar gene set to that induced by phenobarbital, a compound for which pre-treatment is known to confer tolerance to a range of insecticide compounds. The implications of the induction of gene families known to metabolise insecticides and the use of PBO in pest management programs are discussed. Keywords: Induction response after treatment by PBO

2007-03-18 | GSE6144 | GEO

Pleurotus ostreatus

Project description:Pleurotus ostreatus Genome sequencing

| PRJNA252755 | ENA

Transposon-associated epigenetic silencing during Pleurotus ostreatus life cycle

Project description:In this study, we analyzed the genome-wide epigenetic and transcriptional patterns of the white-rot basidiomycete Pleurotus ostreatus throughout its life cycle. Our results performed by using high-throughput sequencing analyses revealed that strain-specific DNA methylation profiles are primarily involved in the repression of transposon activity, and suggest that 21 nt small RNAs play a key role in transposon silencing.Furthermore, we provide evidence that transposon-associated DNA methylation, but not sRNA production, is directly involved in the silencing of genes surrounded by transposons. Finally, we identified key genes activated in the fruiting process through the comparative analysis of transcriptomes.

2018-05-15 | GSE112588 | GEO

Gene age predicts the transcriptional landscape of sexual morphogenesis in multicellular fungi [Pleos]

Project description:Pleurotus ostreatus tissue types and developmental stages

2021-06-05 | GSE176179 | GEO

Pleurotus ostreatus

Project description:Analysis of Pleurotus ostreatus transcriptomes

| PRJNA445337 | ENA

Pleurotus ostreatus

Project description:Pleurotus ostreatus Raw sequence reads

| PRJNA1166743 | ENA