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Effect of Intestinal Microbiome on Chromatin Accessibility in Paneth Cells

ABSTRACT: To assess epigenetic changes, ATAC-seq was performed on Paneth cells isolated from germ-free (GF) and specific pathogen-free (SPF) mice. The results revealed microbiome-dependent alterations in chromatin accessibility at key genomic loci involved in stemness regulation.

ORGANISM(S): Mus musculus

PROVIDER: GSE302951 | GEO | 2026/07/09

REPOSITORIES: GEO

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DNA Methylation and Hydroxymethylation Profiles in Paneth cell from Germ-Free and SPF Mice

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