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Extragenous ILC2s infiltration into the brain after ischemic stroke

ABSTRACT: Group 2 innate lymphoid cells (ILC2s) are key players in immune regulation and tissue repair in barrier immunity, but they are rarely seen in the brain. We investigated whether ILC2s in the peripheral circulation during the acute phase could infiltrate the brain parenchyma. We first transfer ILC2s intravenously into the MCAO mice and performed RNA sequencing of ILC2s isolated from the blood and the brain at different time points after MCAO.

ORGANISM(S): Mus musculus

PROVIDER: GSE302993 | GEO | 2025/07/23

REPOSITORIES: GEO

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