Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

HNRNPH controls alternative splicing cooperatively on a transcriptome-wide scale

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): synthetic construct Homo sapiens

PROVIDER: GSE303138 | GEO | 2026/04/14

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

HNRNPH controls alternative splicing cooperatively on a transcriptome-wide scale [iCLIP]

Project description:To investigate the RNA binding landscape of HNRNPH, we performed an individual-nucleotide resolution UV crosslinking and immunoprecipitation (iCLIP) experiment for HNRNPH in MCF7 cells

2026-04-14 | GSE303135 | GEO

HNRNPH controls alternative splicing cooperatively on a transcriptome-wide scale [RNA-seq]

Project description:To investigate alternative splicing regulation mediated by HNRNPH, we gradually decreased and increased HNRNPH protein concentration in MCF7 cells. Then, we performed splicing analysis using the data from the RNA-Seq.

2026-04-14 | GSE303137 | GEO

HNRNPH controls alternative splicing cooperatively on a transcriptome-wide scale [RTstop profiling]

Project description:High-throughput experimental validation of G-quadruplex formation for RNAs with HNRNPH binding sites is not available. Hence, we performed an in vitro Reverse Transcriptase Stop-Profiling (RT-Stop profiling) in high-throughput to map G-quadruplex structure formation of 2000 individual RNAs that have been identified to be bound by HNRNPH.

2026-04-14 | GSE304967 | GEO

HNRNPH controls alternative splicing cooperatively on a transcriptome-wide scale [in vitro iCLIP]

Project description:The in vitro binding potential of HNRNPH1 to RNA is not available. Hence, we performed an high-throughput in vitro binding assay for recombinant MBP-HNRNPH1 using an RNA oligo library consisting of 2000 individual sequences. We used this in vitro binding assay to map binding of recombinant HNRNPH1 protein to RNA in individual nucleotide resolution. To understand the impact of RNA G-quadruplex structures for HNRNPH1 binding, we compared the binding of HNRNPH1 to GTP RNA and 7-deaza-GTP RNA.

2026-04-14 | GSE304723 | GEO