Gene expression in Tetrahydrocurcumin-treated HUVEC cells

ABSTRACT: Endothelial nitric oxide synthase (eNOS) plays a crucial role in maintaining endothelial cell function and preventing atherosclerosis. Tetrahydrocannabinol is a metabolite that has better bioactivity than curcumin. This study investigated the effect of the PI3K/AKTpathway on eNOS expression and NO production induced by tetrahydrocannabinol (THCu) in human umbilical vein endothelial cells. The findings reveal that both PI3Kand AKT are essential for THC-induced eNOS phosphorylation and subsequent NO production.

ORGANISM(S): Homo sapiens

PROVIDER: GSE303488 | GEO | 2026/02/24

REPOSITORIES: GEO