ScRNA-seq reveals transcriptional profiling of telocytes in synovial tissue

ABSTRACT: This study employs scRNA-seq to characterize Efhd1⁺ tdTomato⁺ telocyte-like cells isolated from knee synovial tissues. By comparing their transcriptional profiles to fibroblasts, we aim to delineate distinct cellular phenotypes and understand telocyte heterogeneity across tissue microenvironments. Our analysis reveals unique gene expression signatures defining telocytes providing insights into their potential roles in tissue homeostasis and fibrosis.

ORGANISM(S): Mus musculus

PROVIDER: GSE303999 | GEO | 2026/02/13

REPOSITORIES: GEO