Transcriptomics

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Genetic and sex-specific regulation of mitochondrial function in gonadal and inguinal adipose tissue


ABSTRACT: Sex differences in adipose tissue impact metabolic health, but the underlying molecular mechanisms remain unclear. We previously identified a female-specific chr17 trans-eQTL hotspot regulating mitochondrial gene expression in gonadal white adipose tissue (gWAT). Here, we tested whether iWAT contributes comparably to sex differences in mitochondrial function and futile cycling.

ORGANISM(S): Mus musculus

PROVIDER: GSE304104 | GEO | 2025/08/05

REPOSITORIES: GEO

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