Genomics

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CTCF (CCCTC-binding factor) binding patterns in the human genome following exposures to Clostridioides difficile TcdB.


ABSTRACT: This experiment uses a CUT&RUN approach to determine if the CCCTC-binding factor (CTCF) is altered in its ability to bind the human genome following exposure to TcdB. TcdB is a bacterial toxin and primary virulence factor produced by the enteric pathogen C. difficile. CTCF is a DNA binding protein that regulates gene transcription in the host.

ORGANISM(S): Homo sapiens

PROVIDER: GSE304121 | GEO | 2026/02/11

REPOSITORIES: GEO

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