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Single-cell RNA-seq of femoral bone cells reveals cellular heterogeneity and molecular mechanisms of chronic intermittent hypoxia-induced bone growth impairment

ABSTRACT: We employed single-cell RNA sequencing to analyze cells isolated from the spongiosa region of the femoral bone in young female mice exposed to chronic intermittent hypoxia (CIH) or normoxia for 4 weeks. This study provides novel insights into cellular heterogeneity and molecular mechanisms involved in CIH-induced bone growth impairment.

ORGANISM(S): Mus musculus

PROVIDER: GSE304165 | GEO | 2026/01/28

REPOSITORIES: GEO

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