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Transcriptomic profiling of irradiated senescent IMR90 cells treated with CDK4/6 or JAK inhibitors

ABSTRACT: Human fetal lung fibroblasts (IMR90) were induced to undergo senescence via ionizing radiation (IR). Ten days post-IR, RNA was collected from proliferating, senescent+DMSO, senescent+Palbociclib (2 µM), and senescent+Ruxolitinib (2 µM) conditions. Cells were treated on Days 4, 6, 8 and 10 after IR. This dataset examines how CDK4/6 or JAK inhibition affects gene expression in senescent cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE304272 | GEO | 2025/08/13

REPOSITORIES: GEO

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