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Single-cell multi-'omic analysis of testis development

ABSTRACT: The developing testis is comprised of multiple cellular lineages, each of which reach developmental milestones at different points in prenatal and neonatal development. To explore how epigenetics shape the developmental trajectories of cellular lineages within the developing testis, we generated a multi-'omic atlas at single-cell resolution (scMultiOme). We discovered that each lineage follows a unique combination of temporally and spatially distinct epigenetic maturation patterns.

ORGANISM(S): Mus musculus

PROVIDER: GSE305215 | GEO | 2026/05/29

REPOSITORIES: GEO

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