Homeostatic Preservation of Action Potential Waveform by Notch and Nerfin-1

ABSTRACT: To understand the homeostatic mechanisms responsible for preservation of neuron type-specific firing we characterized the preservation of neuronal firing following the deletion of a potassium channel gene (Shal/Kv4). Patch-Seq experiments and subsequent genetic analyses reveal widespread Notch signaling-dependent transcriptional changes including a required function for Nerfin-1.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE305311 | GEO | 2026/02/16

REPOSITORIES: GEO