Osteocytic FSH inhibition rescues bone mass and boosts fracture healing in ovariectomized mice

ABSTRACT: RNA-seq of femoral cortical bone from osteocyte-specific Fshr knockout mice (Dmp1-CreERT; Fshrfl/fl) identifies PI3K/Akt pathway activation and enhanced osteoblast-osteoclast coupling underlying increased bone mineralization and accelerated fracture repair in ovariectomized mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE305679 | GEO | 2025/12/01

REPOSITORIES: GEO