Opposing effects of estrogen and Runx2 on breast cancer cell proliferation: identification of a reciprocally-regulated gene signature with clinical prognostic value.

ABSTRACT: Analysis of reciprocal modulation of Runx2 and E2 signaling in BCA. Our objective was to investigate whether the interaction between estrogen and Runx2 signaling in breast cancer (BCa) could help refine an estrogen-responsive gene signature with improved prognostic value.

ORGANISM(S): Homo sapiens

PROVIDER: GSE30597 | GEO | 2012/03/06

SECONDARY ACCESSION(S): PRJNA144569

REPOSITORIES: GEO