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Expression data of porcine mammary glands from late pregnancy to peak lactation.

ABSTRACT: Sow milk yield and quality is crucial for the survival and growth of piglets. Mammary epithelial cell proliferation, differentiation, milk component production and galactopoietic hormone and cytokine synthesis result from the quantities of differentially expressed genes. This study used the Affymetrix Porcine GeneChip to acquire a comprehensive picture of transcriptional adaptations in the mammary glands of lactating sows.

ORGANISM(S): Sus scrofa

PROVIDER: GSE30704 | GEO | 2011/07/16

SECONDARY ACCESSION(S): PRJNA144363

REPOSITORIES: GEO

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Expression data of porcine mammary glands from late pregnancy to peak lactation.

Project description:Sow milk yield and quality is crucial for the survival and growth of piglets. Mammary epithelial cell proliferation, differentiation, milk component production and galactopoietic hormone and cytokine synthesis result from the quantities of differentially expressed genes. This study used the Affymetrix Porcine GeneChip to acquire a comprehensive picture of transcriptional adaptations in the mammary glands of lactating sows. Mammary tissue samples were collected from six sows at -17, 1 and 17 d relative to parturition. Mammary tissues from two sows were used to extract RNA and were subsequently pooled in equal volumes. Nine pooled samples were hybridized to porcine Affymetrix GeneChips.

2011-07-15 | E-GEOD-30704 | biostudies-arrayexpress

Transcriptomics comparisons of Mac-T cells versus mammary tissue during late pregnancy and peak lactation

Project description:The bovine mammary epithelial cell line Mac-T has been used to study mammary gland in vitro. The reliability of this system to study mammary gland has not been tested using genomics approaches. In the present experimetn a direct transcriptomics comparison between Mac-T cells and mammary tissue at -30 and at 60 day in milk (DIM) is performed. Data indicated that Mac-T cells and mammary tissue had a substantially different transcriptome with a larger difference between Mac-T cells and lactating mammary tissue (i.e., 60 DIM) compared to non-lactating mammary tissue (i.e., -30 DIM). In addition, data indicated that the Mac-T cells substantially differ with mammary tissue in lactation-specific functions. cDNA from Mac-T cells induced in vitro into lactation for 36h (addition of prolactin) was directly hybridize in the microarray chip with cDNA from mammary tissue at -30 or 60 day in milk from 3 cows.

2013-04-30 | E-GEOD-46476 | biostudies-arrayexpress

Transcriptomics comparisons of Mac-T cells versus mammary tissue during late pregnancy and peak lactation

2013-04-30 | GSE46476 | GEO

Real-time quantitative PCR analysis of goat mammary glands in peak-lactation and late-lactation periods

Project description:In comparison with cow milk, goat (Capra hircus) milk contains much higher levels of unsaturated fatty acids, as well as higher levels of total fat, proteins, carbohydrates, calcium, and vitamins.The main objective of the present study was to better define the relationship of known miRNAs regulating milk fat metabolism. Our main purpose is to search for some known miRNAs regulating milk fat metabolism, to this end, we screened potential miRNAs with differential expression between peak-lactation and non-lactation.

2016-06-25 | GSE83706 | GEO

Real-time quantitative PCR analysis of goat mammary glands in peak-lactation and late-lactation periods

2016-06-25 | E-GEOD-83706 | biostudies-arrayexpress

Gene Expression in the Human Mammary Epithelium during Lactation: the Milk Fat Globule Transcriptome through 4 Days

Project description:The 4 day gene expression profile in the lactating mammary gland was demonstrated using the Human Ref-8 BeadChip array (Illumina, Inc). Of the 22,184 gene transcripts on the array, 14,070 genes were consistently expressed and represented the milk fat globule transcriptome. Milk protein genes were among the most highly expressed along with genes involved in the milk syntesis processes. Serial milk samples were collected every 3h for 4 days from 5 normal, lactating women. RNA was isolated from the milk fat globules and utilized for microarray analyses.

2011-06-30 | E-GEOD-15208 | biostudies-arrayexpress

Gene expression in the human mammary epithelium during lactation: the milk fat globule transcriptome

Project description:The 24h gene expression profile in the lactating mammary gland was demonstrated using the Human Ref-8 BeadChip array (Illumina, Inc). Of the 22,184 gene transcripts on the array, 14,070 genes were consistently expressed and represented the milk fat globule transcriptome. Milk protein genes were among the most highly expressed along with genes involved in the milk syntesis processes. Keywords: time course analysis

2008-11-25 | GSE12669 | GEO

Comparing gene expression profiles in the mammary glands of high- and low-milk-yield Holstein Friesian cows

Project description:Analysis of key genes and gene networks determining milk productivity of the dairy HF cows Transcriptomes were compared of in the mammary glands of the healthy lactating Holstein Friesian cows of the high- (average 11097 kg milk/lactation) and low- (average 6956 kg milk/lactation) milk yield.

2011-11-16 | E-GEOD-33680 | biostudies-arrayexpress

Gene Expression in the Human Mammary Epithelium during Lactation: the Milk Fat Globule Transcriptome through 4 Days

2011-06-30 | GSE15208 | GEO

Transcriptomic analysis of early IFALD in preterm piglets receiving parenteral nutrition

Project description:Preterm Yorkshire piglets were provided parenteral nutrition for 14 days and developed cholestasis and histologic liver injury. Bottle-fed age-matched controls were provided sow milk replacer every 2-3 hours for 14 days.

2023-08-02 | GSE234108 | GEO

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