Whole-exome sequencing of normal lung tissues, precursor lesions and invasive lung adenocarcinomas

ABSTRACT: Understanding cellular processes underlying early lung adenocarcinoma (LUAD) development is needed to devise intervention strategies. Here, we performed whole exome sequencing (WES) of human treatment-naive lungs comprising various stages in the sequence of pathogenesis of LUAD including normal lung tissues, atypical adenomatous hyperplasia (AAH), adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA) and LUAD.

ORGANISM(S): Homo sapiens

PROVIDER: GSE307529 | GEO | 2025/10/11

REPOSITORIES: GEO