Single-cell RNA sequencing for female Schistosoma mansoni to investigate BATT-induced sexual maturation.

ABSTRACT: Single-cell RNA sequencing (scRNA-seq) was performed on virgin/adult females using 10x Genomics to explore transcriptome change after BATT induction. Egg production by female Schistosoma is central to both the transmission and pathology of schistosomiasis, a neglected tropical disease affecting over 200 million people globally. Female sexual maturation depends on the male-derived pheromone β-alanyl-tryptamine (BATT), yet the molecular mechanisms underlying this process remain largely unknown.

ORGANISM(S): Schistosoma mansoni

PROVIDER: GSE307715 | GEO | 2026/01/28

REPOSITORIES: GEO