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DhQS charged the shikimate pathway pathway in Thermus thermophilus HB27

ABSTRACT: Temperature stress is a survival challenge that biological cells may encounter at any time. To sustain normal metabolic activities, organisms have gradually evolved strategies to respond promptly to temperature changes. The two-component system, typically involved in regulating the transcription of relevant genes in response to environmental stimuli, consists of a histidine kinase and a response regulator. This system mediates environmental signal transduction in microbial cells. This study identified DhqSR as a novel temperature-sensing two-component system in Thermus thermophilus HB27. It regulates the expression of type II 3-dehydroquinate dehydratase (DHQase) in the aromatic amino acid biosynthesis pathway, indirectly controlling aromatic amino acid synthesis and thereby altering cellular thermal adaptation capabilities.

ORGANISM(S): Thermus thermophilus HB27

PROVIDER: GSE307794 | GEO | 2026/02/25

REPOSITORIES: GEO

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DhQS charged the shikimate pathway pathway in Thermus thermophilus HB27

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