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Polyhexamethylene guanidine exposure disrupts protective immunity and accelerates tuberculosis progression via type I IFN signaling and neutrophil influx

ABSTRACT: We investigated the molecular mechanisms by which PHMG regulates host defense in alveolar macrophages against M. tuberculosis infection. To elucidate this, we performed global gene expression analysis of M. tuberculosis infected alveolar macrophages after PHMG treatment.

ORGANISM(S): Mus musculus

PROVIDER: GSE308310 | GEO | 2026/09/03

REPOSITORIES: GEO

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Polyhexamethylene guanidine exposure disrupts protective immunity and accelerates tuberculosis progression via type I IFN signaling and neutrophil influx

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