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CHD3 and CHD4 coordinate gene expression programs to maintain β-cell function and identity in vivo [ATAC-seq]

ABSTRACT: To establish the role of CHD3 and CHD4 on controlling gene expression programs in the beta cell, we generated a tamoxifen-inducible, beta-cell-specific knockout mouse models; control (MIP-CreERT; Chd3+/+; Chd4+/+; R26RtdTomato) and Chd3/4Db (MIP-CreERT; Chd3f/f; Chd4f/f; R26RtdTomato)

ORGANISM(S): Mus musculus

PROVIDER: GSE308381 | GEO | 2026/02/20

REPOSITORIES: GEO

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CHD3 and CHD4 coordinate gene expression programs to maintain β-cell function and identity in vivo [RNA-seq]

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