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RNA-seq of paraventricular thalamus (PVT) and posterior insular cortex (pIC) in a mouse model of STZ-induced painful diabetic neuropathy with anxiety-like behavior

ABSTRACT: We generated poly(A)-selected, stranded mRNA-seq profiles from the paraventricular thalamus (PVT) and posterior insular cortex (pIC) of mice with streptozotocin (STZ; 200 mg/kg, i.p.)–induced painful diabetic neuropathy (PDN) and anxiety-like behavior, alongside vehicle controls. Twenty brain tissue samples (PVT and pIC from PDN and control groups) were sequenced. The dataset enables region-wise differential expression analysis and comparison of convergent versus region-specific remodeling between PVT and pIC.

ORGANISM(S): Mus musculus

PROVIDER: GSE308534 | GEO | 2026/05/30

REPOSITORIES: GEO

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RNA-seq of paraventricular thalamus (PVT) and posterior insular cortex (pIC) in a mouse model of STZ-induced painful diabetic neuropathy with anxiety-like behavior

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