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CHD3 and CHD4 coordinate gene expression programs to maintain β-cell function and identity in vivo

ABSTRACT: To establish the role of CHD3 and CHD4 on controlling human gene expression programs in the islet, we generated pseudoislets from non-diabetic human donors that were treated with shRNA for CHD3, CHD4 or CHD3+CHD4. mRNA-Seq was performed on isolatd RNA from pseudoislets

ORGANISM(S): Homo sapiens

PROVIDER: GSE308785 | GEO | 2026/02/20

REPOSITORIES: GEO

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