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RNA-seq analysis of p62 knockout in murine oral carcinoma MOC2 cells

ABSTRACT: p62/SQSTM1 is an autophagy adaptor protein that regulates stress responses and contributes to tumor progression. To clarify its role in oral cancer, we generated p62 knockout clones of the murine oral carcinoma cell line MOC2 using CRISPR-Cas9. RNA-seq was performed on parental and p62-deficient cells to assess transcriptomic changes associated with p62 loss. The dataset includes raw FASTQ files and processed gene-level count matrices, providing a resource for the study of p62-dependent molecular pathways in cancer biology.

ORGANISM(S): Mus musculus

PROVIDER: GSE309456 | GEO | 2025/12/31

REPOSITORIES: GEO

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