Transcriptomics

Dataset Information

0

Systematic transcriptomic analysis enables targeted drug repurposing for neurotropic flavivirus infections


ABSTRACT: Emerging mosquito-borne orthoflaviviruses like WNV and USUV pose global health risks due to rapid spread, severe neurological effects, and the lack of approved antivirals. This study used transcriptomic and bioinformatic analyses to uncover host–virus interactions and key molecular pathways. Based on these findings, approved drugs with potential antiviral activity were prioritized, and two were selected for experimental validation. The results highlight how integrating transcriptomic profiling with drug repurposing can accelerate the discovery of antiviral strategies against emerging viruses.

ORGANISM(S): Chlorocebus sabaeus

PROVIDER: GSE309915 | GEO | 2026/06/02

REPOSITORIES: GEO

Similar Datasets

2021-01-14 | GSE164788 | GEO
2019-11-14 | PXD011728 | Pride
2018-11-06 | GSE122121 | GEO
2025-11-13 | MTBLS13246 | MetaboLights
2026-01-21 | GSE316780 | GEO
| PRJNA670744 | ENA
2025-01-06 | GSE255795 | GEO
2026-01-06 | GSE256241 | GEO
2017-03-20 | PXD005276 | Pride
2019-09-06 | GSE136342 | GEO