Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptome of TEX cell line following two CDK8 inhibitors treatment

ABSTRACT: TEX cells maintaining functional and phenotypic hierarchy of AML, with leukemia stem cells (LSC) characteristics (PMID: 16094415) was treated with two CDK8 inhibitors (CDK8i) RVU120 (Ryvu) and CCT251921 (Merck), to delineate molecular changes upon CDK8i time course (3h, 24h and 72 hours). There were 984, 4357 and 4257 common differentially expressed genes (FDR <0.05) for both inhibitors with correlation coefficients of 0.82, 0.95 and 0.95, respectively, for 3h, 24h and 72h time points. The dataset generation was supported by the National Science Center grant (2018/30/E/NZ2/00801).

ORGANISM(S): Homo sapiens

PROVIDER: GSE309991 | GEO | 2026/08/13

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Transcriptome of TEX cell line following two CDK8 inhibitors treatment

Project description:Transcriptome of TEX cell line following two CDK8 inhibitors treatment

| PRJNA1364880 | ENA

Brain transcriptome of Larimichthys crocea (Large yellow croaker) under hypoxia

Project description:Brain transcriptome at 0h, 1h, 3h, 6h, 12h, 24h, 48h after hypoxia stress

2015-04-17 | GSE57608 | GEO

Transcriptome profiling of vascular fragments 3h and 24h post MCAO in imatinib and PBS treated mice

Project description:We isolated vascular fragments, representing the BBB, from the ipsilateral hemisphere of imatinib and PBS treated mice 3h and 24h post MCAO induction.

2024-12-01 | GSE137534 | GEO

Hi-C during mitotic release and G1 entry

Project description:DpnII Hi-C libraries for samples synchronized to G2/M using single 24h thymidine, 3h release, and 12h nocodazole--these samples are then released for x amount of time

2019-09-30 | GSE133462 | GEO

IRG1 Inflammasome Proteomics Experiments

Project description:BMDMs of indicated phenotypes were stimulated with LPS for 24h and analyzed or restimulated with LPS for additional 3h and analyzed. In some experiments 1mM itaconate was added at 4h of LPS first stimulation.

2021-09-09 | PXD020089 | Pride

H2AK119ub1 native ChIP-seq upon Xist indution

Project description:Native ChIP-seq for H2AK119ub1 upon Xist induction in iXist-ChrX mouse embryonic stem cells. Comparison of WT with Spen RRM deletion and SPOC domain mutants for two timepoints of Xist induction, 3h and 24h.

2021-07-01 | GSE154549 | GEO

Differentiation time course for Mouse Epiblast Stem Cells

Project description:A time course with 5 differentiation arms was performed, including retinoic acid, BMP4, SB431542, mesoderm and endoderm. RNA-Seq expression profile performed in EpiSC-5 cells at 3h, 6h, 12h, 18h, 24h, 36h, 48h and 72h after treatment.

2025-02-03 | GSE199114 | GEO

Time-resolved gene expression analysis of the astrocyte-derived cell line 1321N1 treated with cadmium, mercury and arsenic.

Project description:To get an insight into the time-resolved gene expression response elicited by different heavy metals, we treated the cell line 1321N1 with cadmium, mercury or arsenic for 1.5h, 3h, 6h, 12h and 24h and performed QuantSeq 3'-mRNA sequencing.

2024-11-16 | GSE281225 | GEO

Identification of androgen-regulated genes in RWPE-1-AR cells

Project description:Transcriptional profiling of RWPE-1 cells stably expressing human androgen receptor (as described in Altintas et al., Mol Cell Endocrinol 2011) treated with a non-metabolisable androgen, R1881 RWPE-1-AR cells were treated with R1881 during 3h or 24h and compared to control not treated cells. Three independent cell culture experiments for each treatment condition (vehicle or R1881 for 3h and 24h).

2011-05-12 | E-GEOD-29232 | biostudies-arrayexpress

Large scale transcriptomic characterization of mice blood inflammation during Acute Lung Injury (PBMC)

Project description:ARN sample of PBMC from mouse were obtened at 6 times points: 1h, 1h30, 3h, 4h, 18H, 24h, after injection of oleic acid or physiological serum PBMC total RNAs from mouse injected with acid oleic or physiological serum were profiled after hybridization with Agilent SurePrint G3 Mouse GE 8x60K Microarray to identify genes with differential expression

2015-01-01 | GSE52684 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data