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Xing-Pi-Qing-Gan decoction alleviates alcoholic liver disease through multi-omics and experimental verification of DDIT3-Nrf2/HO-1-mediated antioxidant defense

ABSTRACT: This study aimed to investigate the transcriptome changes of alcoholic liver disease treated with NIAAA model after administration of Xing-Pi-Qing-Gan decoction. The mice were divided into two groups: one group of NIAAA model mice, and the other group was administered simultaneously on the basis of modeling. After the experiment, total RNA was extracted from fresh liver for high-throughput RNA sequencing (RNA-seq), and the effect of Xing-Pi-Qing-Gan decoction on alcoholic liver disease and related host transcriptional changes were identified by differential gene expression analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE310439 | GEO | 2026/03/18

REPOSITORIES: GEO

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