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Transcriptomic profiling of young, replicative senescent, and premature senescent HUVECs

ABSTRACT: This study compares global gene expression profiles of human umbilical vein endothelial cells (HUVECs) under three conditions: young, replicative senescent, and premature senescent states. RNA sequencing was performed to identify transcriptional changes associated with endothelial aging. The dataset provides gene-level counts and processed expression matrices for downstream analysis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE312006 | GEO | 2026/06/18

REPOSITORIES: GEO

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