Genomics

Dataset Information

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Expression data from anti-EpCAM treated and untreated SP cells compared to lung tissue


ABSTRACT: Targeted therapies against cancer stem cells which are enriched in side populations (SP) involves interruption of Wnt-signalling. Furthermore, EpCAM is a SP marker and modulator of Wnt-signalling. Therefore, the effects of an anti-EpCAM treatment on SP-cells and WNT/β-catenin signalling was studied. SP of the murine lung adenocarcinoma cell line A2C12 was obtained by fluorescence activated cell sorting and whole genome scans helped to define their molecular phenotype after anti-EpCAM antibody treatment.

ORGANISM(S): Mus musculus

PROVIDER: GSE31313 | GEO | 2012/08/08

SECONDARY ACCESSION(S): PRJNA154121

REPOSITORIES: GEO

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