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Ovarian Tumor FAK Inhibition Releases Omega-3 Fatty Acids Stimulating GATA6 Peritoneal Macrophage CXCL13 Production Enhancing Immunotherapy

ABSTRACT: Genetic or pharmacolgic inhibition of Focal Adhesion Kinase in the murine KMF tumor model is compared to the growth of untreated tumors and with those treated with first line or second line chemotherapies. Impact upon the tumor subpopulations and immune compartment is evaluated via scRNAseq..

ORGANISM(S): Mus musculus

PROVIDER: GSE313445 | GEO | 2026/01/06

REPOSITORIES: GEO

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