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RNA exonuclease REXO4 resolves m6A-marked R-loops and suppresses anti-tumor immunity [MRC-seq]

ABSTRACT: To achieve a more specific mapping of m6A-marked R-loops, we developed an m6A-marked R-loop CUT&Tag sequencing (MRC-seq) approach to map m6A-marked R-loops, which involves the specific isolation of R-loops using an S9.6 antibody-based CUT&Tag approach followed by m6A immunoprecipitation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE313848 | GEO | 2026/05/28

REPOSITORIES: GEO

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RNA exonuclease REXO4 resolves m6A-marked R-loops and suppresses anti-tumor immunity [CUT&Tag-seq]

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