Oncolytic vaccinia virus JX-594 demonstrates subtype-specific efficacy and predictive biomarkers in gastric cancer cell lines

ABSTRACT: This project investigates the therapeutic potential of the oncolytic vaccinia virus JX-594 in gastric cancer. We analyzed 49 molecularly characterized GC cell lines and xenograft models, and performed transcriptomic profiling to identify subtype-specific responsiveness and explore predictive biomarkers that may guide clinical application.

ORGANISM(S): Homo sapiens

PROVIDER: GSE314036 | GEO | 2026/04/26

REPOSITORIES: GEO