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Transcriptomic profiling of MCL-1 inhibitor response in lymphoma models in vitro and in vivo

ABSTRACT: This study presents single-cell RNA sequencing (scRNA-seq) profiling of lymphoma models treated with the MCL-1 inhibitor S63845. Human Namalwa lymphoma cellsand mouse Eμ-Myc lymphoma spleen samples were analyzed following vehicle control or S63845 treatment at defined time points to characterize transcriptional responses associated with drug sensitivity, persistence, and resistance.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE314230 | GEO | 2026/03/11

REPOSITORIES: GEO

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