Characterization of DENV E-dimer-Binding Memory B cells and Antibodies

ABSTRACT: We investigated sE-dimer-binding memory B-cell responses in a well-characterized cohort of patients with hospitalized dengue and their subclinical household contacts. Using sE-dimer-binding B-cell staining, single-cell RNA sequencing, and ex vivo single-B-cell cultures, we defined persistence, repertoire features, and antibody functionality of sE-dimer binding MBC

ORGANISM(S): Homo sapiens

PROVIDER: GSE314883 | GEO | 2026/08/05

REPOSITORIES: GEO