Integrated long- and short-read transcriptomics define TRP channel expression in adult mouse cortex

ABSTRACT: Transient receptor potential (TRP) ion channels are polymodal cation channels with well-established roles in peripheral sensory systems, whereas their expression landscape in the adult cerebral cortex remains incompletely defined. This study provides integrated Oxford Nanopore direct RNA sequencing and Illumina RNA-seq datasets from adult mouse cortex, together with Illumina RNA-seq of dorsal root ganglia as a peripheral sensory reference. Three independent cortical biological replicates were profiled on both platforms. These datasets enable quantitative analysis of TRP channel gene- and isoform-level expression, cross-platform comparison of transcript abundance, and full-length transcript characterisation using long-read sequencing aligned to the Ensembl GRCm39 release 115 reference genome. Raw sequencing files and processed gene- and transcript-level expression tables are provided as a resource for transcriptomic analysis of adult mouse neural tissues.

ORGANISM(S): Mus musculus

PROVIDER: GSE315051 | GEO | 2026/04/10

REPOSITORIES: GEO