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Schisandrin B exhibits anti-proliferative effects by inducing ferroptosis in pancreatic cancer

ABSTRACT: Pancreatic cancer (PC) is a lethal malignancy of the digestive system with an extremely low survival rate. Schisandrin B (Sch B) has demonstrated novel pre-clinical antitumor activity in several animal tumor models. However, it remains unclear whether Sch B exerts antitumor effects in PC. The molecular mechanisms underlying the antitumor properties of Sch B were explored using RNA sequencing.

ORGANISM(S): Homo sapiens

PROVIDER: GSE315793 | GEO | 2026/05/21

REPOSITORIES: GEO

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