Hsa_circ_0000818 targets miR-484/HIPK1 axis to ameliorate liver fibrosis by inhibiting Wnt/β-catenin pathway

ABSTRACT: This study sought to identify circRNAs implicated in HF progression and clarify their mechanisms. hsa_circ_0000818 inhibits HF progression by sponging miR-484 and enhancing HIPK1 expression through inhibition of Wnt/β-catenin signaling, making hsa_circ_0000818/miR-484 and its downstream gene HIPK1 potential new therapeutic targets for HF.

ORGANISM(S): Homo sapiens

PROVIDER: GSE316222 | GEO | 2026/06/30

REPOSITORIES: GEO