Vascular smooth muscle cell state trajectories mediate molecular mechanisms of coronary disease risk [Xenium]

ABSTRACT: To investigate the genetic basis of SMC cell state trajectories that underlie the SMC component of CAD causality, we developed a dense timecourse single cell transcriptomic and epigenomic mapping of atherosclerosis in a murine disease model and here present complementary high throughput spatial RNA in situ hybridization data to map transition cell states within the vascular wall.

ORGANISM(S): Mus musculus

PROVIDER: GSE316666 | GEO | 2026/02/25

REPOSITORIES: GEO