Transcriptomics

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Characterisation of thyroid 8505 cells treated with CUET (RNA-Seq)


ABSTRACT: In this study, we examined the impact of copper diethyldithiocarbamate (Cu(DDC)2), a metabolite of the FDA-approved drug disulfiram, on thyroid cancer cells. Mechanistically, Cu(DDC)2 targets valosin containing protein (VCP) – a key regulator of proteostasis – as well as inducing potent transcriptional responses.

ORGANISM(S): Homo sapiens

PROVIDER: GSE317461 | GEO | 2026/02/06

REPOSITORIES: GEO

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