Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mouse kidney cortex: control vs. low sodium diet + captopril treatment

ABSTRACT: miRNA profiling of mouse kidney cortex comparing control vs. low sodium diet + captopril treatment to induce renin expression.

ORGANISM(S): Mus musculus

PROVIDER: GSE31779 | GEO | 2012/02/25

SECONDARY ACCESSION(S): PRJNA145287

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Mouse kidney cortex: control vs. low sodium diet + captopril treatment

Project description:miRNA profiling of mouse kidney cortex comparing control vs. low sodium diet + captopril treatment to induce renin expression. Two condition experiment: control vs treated; biological replicates: individual mice - 3 control, 3 treated. One replicate per array.

2012-02-25 | E-GEOD-31779 | biostudies-arrayexpress

RNA-Seq of baboon kidney cortex biopsies [high sodium diet]

Project description:Blood pressure and the kidney cortex transcriptome response to sodium diet challenge in female nonhuman primates

2022-09-01 | GSE181248 | GEO

Gene induction in mouse C57BL6 kidney cortex by angiotensin converting enzyme inhibition (captopril)

Project description:Attempt to identify genes whose expression changed in the kidney cortex with angiotensin converting enzyme inhibition. Eleven week-old male C57BL6 mice were treated with captopril at 10mg/kg/day in drinking water for 7 days. The kidney cortex was surgically excised and total RNA was isolated using Trizol (Invitrogen) from three treated and three control mice and was further purified using RNeasy MinElute Cleanup spin columns (Qiagen) according to manufacturer’s instructions. Probes generated from the resulting RNA were hybridized to Illumina Expression BeadChips (mouseWG-6_V2).

2014-10-02 | E-GEOD-57239 | biostudies-arrayexpress

Gene expression profiles of renin producing cells in the adult kidney (captopril treated animals) isolated from Renin-YFP transgenic mice using FACS (GUDMAP Series ID:46).

Project description:The long term objective is to create an encyclopedia of the expression levels of all genes in multiple components of the developing kidney. The central thesis is straightforward. The combination of fluorescent activated cell sorting (FACS) plus microarray analysis offers a powerful, efficient and effective method for the creation of a global gene expression atlas of the developing kidney. Microarrays with essentially complete genome coverage can be used to quantitate expression levels of every gene in FACS isolated components of the developing kidney. The ensuing rapid read-out provides an expression atlas that is more sensitive, more economical and more complete than would be possible by in situ hybridizations alone. Renin-YFP transgenic mice were utilized to isolate renin producing cells from the kidneys of Adult mice treated with captopril, which was provided in the drinking water at a concentration of 0.5mg/ml. In addition, mice were given low-salt chow. Mice were treated for two weeks before renin producing cells were isolated from the kidney by fluorescent activated cell sorting (FACS). RNA was isolated from FACS sorted cells and the gene expression profiles were determined by microarrays.

2012-12-05 | E-GEOD-42712 | biostudies-arrayexpress

Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC)

Project description:We report the changes in miRNA expression in the renal cortex od the PCK rats fed diets with different sodium content

2019-05-24 | GSE131693 | GEO

Gene induction in mouse C57BL6 kidney cortex by angiotensin converting enzyme inhibition (captopril)

Project description:Attempt to identify genes whose expression changed in the kidney cortex with angiotensin converting enzyme inhibition.

2014-10-02 | GSE57239 | GEO

Microarray gene expression profiling of aorta genes of APOE-deficient mice receiving the ACE inhibitor captopril

2009-12-03 | GSE19286 | GEO

Mus musculus

Project description:Mouse kidney cortex: control vs. low sodium diet + captopril treatment

| PRJNA145287 | ENA

Heart Failure, DITPA and Captopril

Project description:Three weeks after infarction, age matched rats with large infarction by ECG criteria were randomly assigned to one of the three groups: 1) Treatment with Captopril for 21 days and a daily subcutaneous dose of DITPA for the last 10 days of treatment, 2) Treatment for 10 days with DITPA alone, 3) Control heart failure and 4) Sham-operated. Keywords: Drug Effects on Heart Failure

2006-07-21 | GSE4963 | GEO

Transcription profiling of mouse aorta genes of APOE-deficient animals receiving the ACE inhibitor captopril

Project description:Microarray gene expression profiling of aorta genes of APOE-deficient mice receiving atherosclerosis treatment with the ACE inhibitor captopril. Hypercholesterolemic APOE-deficient mice were used as a standard model of atherosclerosis to study gene expression changes during atherosclerosis treatment with the ACE inhibitor captopril. Microarray analysis was performed of whole aortas isolated from captopril-treated APOE-deficient mice relative to untreated APOE-deficient mice with overt atherosclerosis, and nontransgenic control mice. Microarray gene expression profiling revealed that captopril-mediated atherosclerosis prevention involved inhibition of aorta-infiltrating immune cells such as pro-atherogenic T lymphocytes and macrophages. Experiment Overall Design: Microarray gene expression profiling was performed of whole aortas isolated from APOE-deficient mice with atherosclerosis relative to captopril-treated APOE-deficient mice, and nontransgenic control mice. Three study groups were analyzed, i.e. 8-months-old untreated APOE-deficient mice with overt atherosclerosis, age-matched APOE-deficient mice treated for 7 months with the angiotensin-converting enzyme (ACE) inhibitor, captopril (20 mg/kg in drinking water), and nontransgenic control C57BL/6J mice. Two biological replicates were made of each group, and total RNA of three aortas was pooled for one gene chip.

2009-12-14 | E-GEOD-19286 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data