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Ribo-seq analysis analysis of SNU-668 Erastin-resistant cells transfected with shRNA-ALKBH3 or control shRNA

ABSTRACT: This study presents a comprehensive ribosome profiling (Ribo-seq) analysis conducted on SNU-668 gastric cancer cells with acquired resistance to Erastin. These cells were genetically modified through stable transfection with either a short hairpin RNA (shRNA) construct specifically targeting and knocking down the expression of the ALKBH3 gene, or a corresponding non-targeting control shRNA, to systematically investigate the consequent alterations in global translational activity.

ORGANISM(S): Homo sapiens

PROVIDER: GSE317885 | GEO | 2026/02/02

REPOSITORIES: GEO

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