H4K20me1 and gene expression in adult myocyte hypertrophy

ABSTRACT: The lysine methyltransferase KMT5A is shown to mediate the effects of CDC14A in the adult cardiomyocyte by regulating H4K20 mono-methylation, such that reduced KMT5A expression promotes a phenotype resembling Dilated Cardiomyopathy.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE318470 | GEO | 2026/02/18

REPOSITORIES: GEO