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ST8Sia6-dependent glycosylation restrains gut inflammation and pathogenic Th1 and Th17 programs

ABSTRACT: Single-cell suspensions of small bowel lamina propria, small bowel epithelium, and whole colon were purified from mice sufficient, deficient, and heterozygous for sialic acid transferase ST8Sia6. Cells were enriched for CD45 expression, hashtagged according to genotype, and analyzed by 10x scRNA sequencing using the Illumina Novaseq 6000 as well as by 10X CITEseq to identify hashtags.

ORGANISM(S): Mus musculus

PROVIDER: GSE318707 | GEO | 2026/03/22

REPOSITORIES: GEO

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ST8Sia6-dependent glycosylation restrains gut inflammation and pathogenic Th1 and Th17 programs

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