Single-cell RNA-seq of human non-lesional whole skin adjacent to an invasive melanoma excision scar, 5cm from the scar biopsy, and at a distant photoprotected site

ABSTRACT: Potentially carcinogenic mutations are widespread throughout the skin, and it is unknown why only some sites develop into a malignancy while most others continue to function normally. Using 10x Genomics Chomium Flex scRNA-seq, we explored differences in skin with similar levels of photodamage adjacent to and proximal to (5cm away from) a melanoma excision scar, and distant photoprotected skin.

ORGANISM(S): Homo sapiens

PROVIDER: GSE318899 | GEO | 2026/06/09

REPOSITORIES: GEO