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In Vivo inhibition of TDO2 in fibroids results in widespread alteration in the tumor transcriptome

ABSTRACT: This study aimed to characterize large and small RNA transcriptomic changes in fibroid xenografts from mice treated with the TDO2 inhibitor 680C91 for two months.

ORGANISM(S): Homo sapiens

PROVIDER: GSE319228 | GEO | 2026/02/16

REPOSITORIES: GEO

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In Vivo inhibition of TDO2 in fibroids results in widespread alteration in the tumor transcriptome

Project description:In Vivo inhibition of TDO2 in fibroids results in widespread alteration in the tumor transcriptome

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TDO2 promotes hepatocellular carcinoma by regulating tryptophan-kynurenine pathway

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Transcriptome and DNA Methylome Analyses Reveal Underlying Mechanisms for the Racial Disparity in Uterine Fibroids [EPIC Human Methylation Array]

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