Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Comparative microarray analysis of skin transcriptomes from patients with atopic dermatitis and healthy controls

ABSTRACT: Microarray-based gene expression profiling was performed on skin samples from patients with atopic dermatitis and healthy controls to analyze disease-associated transcriptional differences.

ORGANISM(S): Homo sapiens

PROVIDER: GSE320223 | GEO | 2026/07/21

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Comparative microarray analysis of skin transcriptomes from patients with atopic dermatitis and healthy controls

Project description:Comparative microarray analysis of skin transcriptomes from patients with atopic dermatitis and healthy controls

| PRJNA1427171 | ENA

Microarray transcriptome profiling of atopic dermatitis and psoriasis patients compared to healthy volunteers.

Project description:Characteization host-microbiome interactions in patients with allergic (model: atopic dermatitis) and autoimmune (model: psoriasis) diseases by integration of microarray transcriptome data with 16S microbial profiling. 6mm punch biopsies were collected from the skin of atopic dermatitis and psoriasis patients alongside healthy volunteers, and subjected to analysis using Affymetrix Human Gene ST 2.1 arrays.

2019-09-11 | E-MTAB-8149 | biostudies-arrayexpress

Microarray result of human skin derived from normal, atopic dermatitis and atopic march patients

Project description:The patho-mechanism of atopic dermatitis showing systemic involvement may be explained by Th17-related cytokines induced by FABP5 through systemic sensitization to a major allergen of a house dust mite.

2020-03-05 | GSE146352 | GEO

Genome-Wide Profiling of Lesional and Non-Lesional Skin from Atopic Dermatitis, Psoriasis, and Contact Dermatitis Skin

Project description:Genome-Wide Profiling of Lesional and Non-Lesional Skin from Atopic Dermatitis, Psoriasis, and Contact Dermatitis Skin

2020-06-23 | GSE153007 | GEO

Skin Microbiome in Atopic Dermatitis

Project description:Skin Microbiome in Atopic Dermatitis

| PRJEB21789 | ENA

MicroRNA expression data from skin samples of adult atopic dermatitis and psoriasis patients and healthy controls

Project description:Atopic dermatitis (AD) and psoriasis vulgaris (PV) affect up to 3-5% of adults in developed countries and severely impair their quality of life thorough adulthood. MicroRNAs contribute to either the development or regulation of several diseases and are present in tissue. Although several miRNAs have been associated with AD or PV, to our knowledge, scarce studies have been published to date of miRNA profiling comparing AD and PV patients.

2023-01-03 | GSE175438 | GEO

mRNA expression of Atopic Dermatitis keratinocytes

Project description:mRNA array analysis of total RNA from primary kertinocytes from three healthy controls, three atopic dermatitis patients and three psoriasis patients was carried out

2012-06-01 | E-MTAB-728 | biostudies-arrayexpress

Gene expression data from healthy controls and atopic dermatitis patients skin

Project description:Gene expression data from healthy controls and atopic dermatitis patients skin

| PRJNA513133 | ENA

Genomic profiling of the overlap phenotype between psoriasis and atopic dermatitis

Project description:Clinical overlaps between psoriasis and atopic dermatitis are sometimes undiscernible, and there is no consensus whether to treat the overlap phenotype as psoriasis or atopic dermatitis. We enrolled patients diagnosed with either psoriasis or atopic dermatitis, and clinically re-stratified them into classic psoriasis, classic atopic dermatitis, and the overlap phenotype between psoriasis and atopic dermatitis. We compared gene expression profiles of lesional and nonlesional skin biopsy tissues between the three comparison groups. Global mRNA expression and T-cell subset cytokine expression in the skin of the overlap phenotype were consistent with the profiles of psoriasis and different from the profiles of atopic dermatitis. Unsupervised k-means clustering indicated that the best number of distinct clusters for the total population of the three comparison groups was two, and the two clusters of psoriasis and atopic dermatitis were differentiated by gene expression. Our study suggests that clinical overlap phenotype between psoriasis and atopic dermatitis has dominant molecular features of psoriasis, and genomic biomarkers can differentiate psoriasis and atopic dermatitis at molecular levels in patients with a spectrum of psoriasis and atopic dermatitis.

2023-06-24 | GSE182740 | GEO

Bulk RNA-seq of Peripheral Blood Mononuclear Cells from AmaXhosa Children with Atopic Dermatitis and Healthy Controls in Rural and Urban South Africa

Project description:This RNA-seq experiment profiles peripheral blood mononuclear cells from AmaXhosa children aged 12–36 months with clinically diagnosed moderate-to-severe atopic dermatitis and matched healthy controls living in rural or urban South African settings. The main goal is to capture systemic immune transcriptional programs associated with early-life atopic dermatitis while accounting for the strong contextual influence of environment. By comparing disease status across rural/urban strata, the dataset is designed to distinguish disease-linked expression patterns from location-associated immune signatures, and to identify gene sets reflecting pathways plausibly involved in atopic inflammation, barrier/immune regulation, and related mechanisms. The resulting transcriptomic signatures are intended for downstream integration with cytokine and antibody measurements and environmental exposure data to support mechanistic interpretation and endotype definition.

2026-03-03 | E-MTAB-16535 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data